What is Active Pharmaceutical Ingredients (APIs)?

Pharmaceutical active ingredients, often called APIs for short are the biologically active substances in pharmaceutical formulations that produce the intended therapeutic effects. They are the key components that provide the medicinal benefits for the drug designed to deliver. Active ingredients are carefully selected and formulated to treat specific conditions or illnesses. They can be derived from various sources, including natural products like plants, microorganisms, or animal sources, or can be synthesized in a laboratory. The development of APIs involves extensive research and testing to ensure their safety, efficacy, and optimal dosage for the intended use.

Why can we become your reliable choice?

Miedykol® is a Chinese brand we created in 2020 under its parent US company Mikem Chemical Ltd., Co. This brand that continues to carry our aspirations to better lives via the green chemicals, specializes in pharmaceutical fields so as to integrate our industry chain and business units with the cellulose and starch ether products at its core. Earlier from 2015, we just started to plan the presence in the market of active pharmaceutical ingredients and pharmaceutical intermediates. With the nearly decade of development, we come to maturity at every aspects, so we decide to build another brand—Cysolvia® featuring our high-end APIs and their intermediates unit, and to incorporate the brand into our pharmaceuticals-focused company—Miedykol®, along with our pharma cellulose brand—Mikecello^TM and Becis^TM.        

1. The course of development of Cysolvia®

Around in 2014-2015, we researched and discovered the huge potential in the market of high-end active ingredients and their intermediates. Combined our existing industrial advantages, we set about to invest in producing those mature and widely acknowledged products including some anti-inflammatory elements for eye drops and and ingredients for calcium channel blockers (CCBs). In 2016, our annual production capacity of NSAIDs-class components and CCBs-type ingredients had reach to 1-2 MT, and the sales market mainly focused on the domestic. 

Obtaining the positive feedback for our products, we continued to invest more in laboratory, equipment and talent resources. Between 2016 and 2022, the well-developed active ingredients plus intermediates produced from laboratory have been more than 50 kinds. And increasingly, we began to put our attention to the global market.

In 2024, we officially created and registered the the brand name “Cysolvia” which signifies the brand offerings and focus areas. It has been integrated in our Miedykol® Biopharma Sci & Tech Ltd. as an independent business division to formally provide the integrative service for our global partners.

2. What makes the brand competitive?

Under the nowadays’ changing and uncertain international situations, each market entities are facing the unprecedented survival stress. With the human beings’ evolving demands and the endless technological transformation, the competition is increasingly fierce among the mainstream markets. We in depth understand this reality and have been full prepared for against all possible risks.       

Strong ability to resist risks

We started the business with the construction-grade cellulose ether products using the name of Melacoll under Mikem Chemical. As the domestic market increasingly become saturated, we expanded our business abroad. During the pandemic, we devoted all efforts into cost reduction and benefit increasing, curtailing unnecessary expense in manufacture, research and development of new products, improving production efficiency and doing the best what can control. Meanwhile, our leadership promptly transformed the business mode, and proactively explored the new opportunities and racing tracks. In the aftermath of pandemic, hence, we instead become stronger than the previous. The production capacity and efficiency has further increased, our brands are recognized worldwide, and increasing suppliers and distributors in the upperstream and downstream industry have sought long-term cooperation with us.    

Adopting sustainable strategic investment

To avoid the blindness in investment and expansion, the leadership responsible for the project of financing and investing adopts the sustainable strategy by going deeply to explore the key point of the increasing demands and making the detailed market analysis. From learning to exceeding, the sustainable philosophy has ensured us every step is solid.   

Projecting in advance

From a small firm to an international corporation, our growth benefits from the planning ahead. We take our advantage product—cellulose and starch ether as a core to conduct the industrial radiation; through the industrial development reports, we actively seek the novel growth pole and present the new project, and adjust promptly according to the market feedback.

Diversifying the product portfolios

As a customer-focused manufacturer, we refuse to simplify the offerings. During the course of development, our product system has been built more and more in line with the needs of the market. We also adopt the diversifying pricing strategy to meet the needs at different levels.   

Stringent quality control

Quality is our lifeline. Miedykol spares no efforts to ensure every product must align with or even exceed your expectation. Your satisfaction is the cornerstone for our growth. We assure every order with the strictest quality control measures.

Miedykol® follows the laws and regulations to implement uncompromising quality standards. From formula to production procedure and to packaging, every step contributes to our final result. 

A final inspection is conducted prior to the logistics process. We consistently perform thorough checks, even going beyond to ensure that every product we deliver meets the 100% Miedykol® quality standards. With the efficiency-focused factory and logistics condition, we are committed to dispatching your orders within the agreed-upon timeframe.

3. How does the brand serve our partners?

Cysolvia® is a brand specialized in the field of active ingredients and synthesized intermediates supplying for the pharmaceutical enterprises or for the institute devoted in pharmaceutical experiment, research and development. This brand stands for our high-quality API products and customized service, which include:

The standard-compliant active ingredient products

For now, we can provide the standard products for their common corresponding dosage forms, such as pranoprofen, bromofenac sodium, amfenac sodium, loteprednol etabonate, cilnidipine, mitiglinide calcium hydrate, stiripentol (See more). The active content of all the products can reach to 98-99%, their storage is also stringently compliant with the storage standard for APIs. Our products enjoy stable quality which is unaffected by packaging materials or storage conditions.

The customized production

With the rich experience in CMO/CDMO project management, we strive to build Cysolvia® into a solution-based brand rather than a simply product provider. To this end, we have been capable of meeting the specific needs in a diversity of formulations and there have been our successful cases.

4. What is the future development of Cysolvia®?  

With the vision of empowering the global pharmaceutical industry, Cysolvia® as an active ingredient manufacturer will devote the endless efforts throughout the production, service, research and development, packaging and logistics.

As one of important business divisions of Miedykol®, Cysolvia® is expected to make more breakthroughs in the following aspects:

Deeply excavating market needs.

We will build a collaborated system specialized in market research through the deep cooperation among salespersons, product manager, chief engineers and marketing personnel. Precisely align with needs and take advantage of laboratory to produce what the market really wants.  

Improving ability of research and development.

By the way of encouraging our technicians to attend more academic seminars and communication conferences. Encourage the young researchers to publish more research papers.   Investment will be increased in self research and development of the novel active ingredients. Possess more patented and proprietary technologies, and achieve mass production to further reduce the cost.     

Upgrading the technical proficiency.

We will closely keep pace with the latest research results internationally and try to achieve mass production within the shortest time.     

Improving the one-stop service.  

We will offer our global customers the improved and reliable integrative solutions from formula, to production process and to packaging and logistics.

How to discuss with us your needs?

We are committed to serving your specific demands with the prompt response. Here are some cost-efficient methods for you to discuss with us your needs:

Online customer service. You can click the hovering icon for whatever you want to inquire. 

Send an e-mail. Writing a detailed e-mail to us about your specific needs via the address: sales@mikem.com; miedykol@mikem.com

At Whatsapp: +86 15562605588 (Ella Yang, Senior Business Manager)

WeChat QR Code: If you have WeChat account, you can directly scan the following QR Code and add our Senior Business Manager Ella Yang: