Both the natural cellulose and starch are decomposed into glucose after hydrolysis, and hence they are also called natural plant polysaccharide. Modified cellulose and starch, also the cellulose and starch derivatives are one of the most popular excipients for pharma. These modified biobased polymers are often multifunctional, acting as a binder, thickener, stabilizer, disintegrant, film forming and coating agent in oral dosage or topical forms. Sourcing from nature, these polymers will safely improve the bioavailability of medicines, reduce the usage of other materials, control the speed and position of releasing, and diversify the administration route.